Syndrome X – the most prevalent of metabolic disease in the world, affects almost 70% of the western population between ages 50 and 65 – making it the most dangerous health potential on the planet (3). Hence – it comes as no surprise to learn that mostly, those seeking help at Southbroom Wellness are suffering from some or other systemic or metabolic disorder. 

Collectively, Syndrome X is responsible for cardiac disorders, acidosis, diabetes mellitus type 2, obesity, ovarian cysts, cystitis, Alzheimer’s, dementia and fatty liver disease, cancer, chronic fatigue syndrome, GERT, depression, to name but a few. As a matter of fact – the cumulative result of a life style devoid of good dietary habits, essential nutrients, exercise and moderate alcohol consumption is Syndrome X. 

What is worse is that it is common knowledge that existing allopathic management strategies are not effective in controlling the condition, and that only natural supplementation and life style changes may make a meaningful difference. (1, 2) 

Fighting the specific components of this syndrome has therefore become one of the most important public health initiatives in Western Society. In particular, the increasing global strategies against obesity are not comprehensive in its tactics -  research has shown that current dietary guidelines require modification, with revised dietary guidelines and the help of key dietary supplements or functional foods, including orthomolecular substances, being the only effective strategy. (1, 2) 

Our first article dealt with systemic acidosis – to make the reader aware of the importance of pH balance. This article will now take the argument further – explaining syndrome X, and how it is caused by life style related habits, which includes alcohol use, stress, diet, nutrition and lack of exercise.  

The onset of Syndrome X is progressive – it creeps up on us unnoticed. When it is almost too late, we then seek help. The cause, again – is a positive charge in body fluids, which means sluggish flow of nutrients and systemic lack of oxygen (hypoxia). This will cause the blood to be carbon dioxide rich resulting in acid pH. When the blood becomes acid – the heart battles because it has a lack of base minerals (calcium, potassium, magnesium, zinc, copper) and the normal “nutrient pumps” do not function as intended.  

Calcium is now leached from the bones to support heart function, and the result is deficiencies of base minerals that controls cardiovascular homeostasis, bone density and pH. The body – in this compromised position, is literally waiting for a malfunction to happen. These malfunctions can arise anywhere in the circulatory system – in other words, it is systemic. The total body is thus at risk, and if homeostasis and metabolism is not corrected – especially that of the gastro-intestinal tract (absorption, peristalsis) and cardiovascular system (negative charge of blood platelets), serious life threatening conditions may arise.  

Nutrition, brain functioning and cardiovascular health will suffer as a result.  

So what is the probable cause of Syndrome X? Apart from the known causes (diet, lifestyle, smoking, lack of exercise and alcohol abuse) new studies show that it may be the thyroid gland, which may be responsible for Syndrome X.(5) Also shown in other studies is that Syndrome X is always accompanied by low levels of insulin and pre-diabetic conditions. If we consider that diabetes is associated with obesity and thyroid metabolism imbalance, a lack of iodine may be the culprit. 

Yet another study has found a direct link between thyroid imbalance, cardiac disease and depression.(6) We now have a direct link to the most prevalent symptoms of Syndrome X and Iodine. 

Iodine – the forgotten supplement, is directly responsible for human metabolism and endocrine system functioning – and sadly, we lack it. Very few health practitioners are iodine literate, and in general, it remains ignored unless you have an over active or under active thyroid function. The reason is simple – iodine has been removed from the western diet.  

There is an epidemic of Iodine deficiency, one that affects every man, woman and child – especially vegetarians. Over the last 30 years our Iodine intake has declined 50% (removed from our food supply, especially the baking industry), while the ingestion of toxic competing halogens (bromine, fluorine, chlorine, perchlorate) has dramatically increased in food, water, medicines and the environment (Iodine in wheat has been replaced with Bromine, the gas used to fumigate your house for termites). Simultaneously there has been a related increase in the rates of thyroid disease, breast cancer, fibrocystic breast disease, diabetes and cardiovascular disease. 

The Wolff-Chaikoff experiment led to a fear of iodine, and iodine being removed from the American food supply for over 30 years, followed by other western nations.  

This scientific paper has been quoted by many, but understood by few. It was (and still is) misinterpreted, and used to describe a case of hypothyroidism caused by excessive radioactive iodine intake. In fact: toxic radioactive iodine was injected intravenously in subjects, and the experiment had nothing to do with food or iodine supplementation. 

In the case of bromine – now used in baking instead of iodine – the effects are even more disastrous. 

Bromine is a poison, and has no place in food for human consumption.  As a gas it is used to tent a house and kill termites.  Bromine is close in size to iodine, and can bind to iodide receptors in the thyroid blocking their function.  Bromine has been substituted for iodide in many foods, medications and the environment – despite the fact that it is a pesticide.  It has replaced iodide in all bakery products, reducing our iodide intake by 726 mcg/day.  

The ingestion of bromine (or breathing bromine gas) in an iodine-deficient state will further exacerbate thyroid illness.  Bromine intoxication symptoms include: feeling dull, apathetic, depressed, irritable, and headachy, and may lead to hypothyroidism.  Severe reactions include delirium, psychomotor retardation, schizophrenia, and hallucination.  Bromine also binds to and damages the iodide SIS transporter (sodium-iodide symporter) mechanism. 

Sources of bromine include food (baked and canned goods), medication, soft drinks, energy drinks and chemicals like pool cleaners and pesticides. Bromine is classed as a halogen. Halogens are a class of related elements that include iodine, bromine, fluorine and chlorine. When they are chemically reduced they become halides: iodide, bromide, fluoride, and chloride.  

These are the forms we usually encounter in foods, medications and the environment.

While iodine and chloride are beneficial in small amounts, the others are toxic. They bind to iodine receptors, blocking the action of iodide and thyroid hormones, and cause many severe diseases.  

Toxic halides excrete very slowly from the body, because there is no known liver detoxification pathway for them. Excretion can be increased with high-dose iodine (lugols), high-dose vitamin C (which aids detoxification), unrefined sea salt (which substitutes chloride for bromide), Epsom salts baths, sweating in a dry heat infrared sauna, MSM and EDTA. 

Nu-Life Wellness has pioneered the use of these agents in the fight against Syndrome X. When combined with sodium bicarbonate in the correct formulation, it becomes one of the most powerful natural allopathic combinations on the planet. 

Bromine has now been banned for use in Canada, the United Kingdom and Europe, which is cause for rejoicing. 

Syndrome X thus seems to be linked to bromine toxicity, iodine deficiency, diet, lifestyle, alcohol use, lack of exercise and stress. The facts are clear and the clinical studies are there to support this hypothesis. Yet – mostly people and health practitioners prefer to ignore this problem.  

Wellness is and integrated science – it means total body/mind/spiritual health.

Becoming aware of epidemics like Syndrome X and related conditions, and the underlying causes can put us in a position to make informed choices. For the fight against breast cancer, woman should consider Lugols iodine as a supplement. Studies suggest that iodine does not cause breast cancer, and that HRT therapy is quite safe combined with iodine supplementation. 

Fighting Factor X is thus done with more than changing our life style – it is an integrative approach, which will affect our lives profoundly, and our health even more so. However hard it may seem – the trade off is that you can literally reverse the condition in just eight weeks. Although the condition can be reversed, dread disease – if already manifest, cannot. (4) 

Life style and diet changes are therefore also a prevention strategy – to prevent the onset of age related disease. Factor X is the single most dangerous health condition in Western society, and ignoring it is plain stupidity. Mostly – the focus in complimentary alternative medicine in fighting Syndrome X is on iodine deficiency and restoring negative charge in the circulatory system, for which there is ample evidence. 

Common symptoms of Syndrome X are as follows: 

Chronic fatigue
Arthritic pains
Shortness of breath
Mild depression
Brain fog
Gastric reflux
Stiffness of joints
Weight gain
Cancer (breast, prostate, ovarian and colon)
Systemic Candidiasis
Irritability and short temper
Unhealthy red glow to the skin
Skin lesions and canker sores
Burning urine
Difficulty urinating
Bladder infections
Low calcium, zinc and copper levels
Recurring MRSA infections (methicillin-resistant Staphylococcus aureus)
Herpes zoster (shingles)
Herpes (cold sores)
HHV virus’ (Epstein Barr, Mineures) 

If you suffer from a combination of some of these symptoms – it is best to consult with a health care practitioner that is Syndrome X literate. 

As a responsible public – we should take note of these “unseen” conditions and align our own health strategy with that of the WHO (World Health Organization)  - as should all health practitioners. As community care-givers, health practitioners should play an active role in making the general public aware of Syndrome X, as well as align their treatment protocols to reflect a holistic strategy that targets cause – not symptoms. 

In good health 


Nu-Life Wellness Centre Copyright 2013 


1.  Holt, S. Combat Syndrome X,Y anf Z.. Newark, NJ: Wellness Publishing 2002

2.  Holt, S, Wright JV, Taylor TV. Syndrome X Nutritional Factors. Newark, NJ.ellness     Publishing, 2003 (in press)

3.  Ford ES, Giles WH, Dietz W. The prevalence of metabolic syndrome in the US population. JAMA 297(3):256-359, 2002

4.  Holt, S. The Soy Revolution. New York: Dell Publishing Inc. 1999

5.  Avturk S. et al. Metabolic syndrome and its components are associated with increased thyroid volume and nodule prevalence in a mild-to-moderate iodine-deficient area. Department of Endocrinology and Metabolism, Baskent University Faculty of Medicine, 5 Cadde No. 48, 06490 Bahcelievler, Ankara, Turkey. Pub MedJuly2009                                                                                                                                                      6.  Bunevicius R. et al:Depression and thyroid axis function in coronary artery disease: impact of cardiac impairment and gender. Institute of Psychophysiology and Rehabilitation, Kaunas University of Medicine, Palanga, Lithuania. 2006